Analytical Pharmacokineticist, small biotech, Boston, MA, Position 433

POSITION DESCRIPTION:

Client is seeking a talented, highly motivated analytical pharmacologist to join the Bioanalytical Sciences group. The successful applicant will become part of cross-functional teams in support of Client's therapeutics.

BASIC RESPONSIBILITIES:

• Development, qualification and use of LC/MS/MS bioanalytical methods for multiple development programs.
• Analysis of pharmacokinetic and toxicokinetic data using WinNonlin software
• Management of outsourced GLP analytical studies, evaluation and auditing of contract research labs, facilitating LC/MS/MS method transfer, and reviewing GLP validation reports.
• Supervise and mentor research associates.
• Report writing for IND submissions and related documents

QUALIFICATIONS:

• A BS/MS with 10+ years experience or a PhD with at least 5 years relevant experience in analytical chemistry, pharmacology or equivalent
• Experience with HPLC and mass spectrometry is required
• Experience in a GLP environment is a plus.
• Excellent written and oral communication skills with an attention to detail

BASIC RESPONSIBILITIES:
• The successful candidate will manage and provide technical leadership for a growing bioanalytical team.
• This individual will serve as the principal liaison to several product-focused teams, which are comprised of individuals with backgrounds in microbiology, genetic engineering, and fermentation process development.
• This candidate will be responsible for proactively implementing plans to ensure that bioanalytical resources and capabilities meet the needs of the project teams.
• The activities of the bioanalytical group, in conjunction with project teams, will help define fundamental mechanisms that regulate the production of specific microbial metabolites.
• This candidate will configure biochemical and bioanalytical assays to enable high-throughput quantification of metabolites from complex fermentation samples.
• These assays will require the ability to develop methods for the robust detection of both intra- and extra-cellular metabolites.
• A critical responsibility of the successful candidate will be to effectively communicate and make recommendations both with fellow team members, internal management and external partners.

QUALIFICATIONS:
• Ph.D. with 2+ years of relevant experience is required; industrial experience is a plus.
• This position requires working knowledge of various methods for the physical characterization of small molecules, including HPLC and mass spectrometry.
• The ideal candidate will have biochemical experience in the context of microbial metabolic engineering projects.
• The candidate must have excellent communication skills and the ability to exercise independent judgment.
• A key to succeeding in this organization is the willingness and ability to perform as a team member in a smaller collegial work environment.
Education: M.S. / Ph.D.

Please email your CV/Resume to cv@mspeople.net