High Throughput Bioanalytical Leader, Principal or Senior Principal Scientist, Northeast Pharmaceutical Company, Position 442

POSITION DESCRIPTION:

The successful candidate will work within a core ADME technology group and lead an early drug discovery bioanalytical laboratory performing quantitative and qualitative analysis of in-vitro ADME samples supporting therapeutic area research projects and specialized assays.  This position requires a willingness and ability to perform as a team member with complementary biology labs to develop, implement and organize ADME biology/biochemistry studies. 

RESPONSIBILITES:

· Guide 4-6 scientists and oversee day to day operations of a bioanalytical laboratory
(includes adhering to appropriate safety and policy procedures and reagent/supply ordering)

· Design, develop and implement bioanalytical methods (primarily liquid
chromatography/tandem mass spectrometry) to qualitatively and/or quantitatively determine
drug compounds in in-vitro biological matrices

· Ability to validate new bioanalytical methods by applying sound scientific principles

· Biochemical and analytical operation of several in-vitro assays

· Ensure data quality and turnaround time is of a standard suitable for the needs of partnering colleagues

· Evaluation and implementation of new analytical/bioanalytical technologies

· Work within the broader organization to develop and implement new technologies which
may include in-vitro assays, analytical advances, imaging, etc

QUALIFICATIONS:

MINIMUM:

· M.S. 5-7 years, Ph.D. 2-5 years working in an industrial bioanalytical chemistry laboratory

· Demonstrate a depth of scientific and technical knowledge in the area of liquid chromatography and mass spectrometry commensurate with current experts in the field

· Possess strong communication and writing skills

· Strong ability to manage several projects simultaneously

· Capable of managing work activities (timelines and schedules)

· Ability to work effectively and comfortably in a matrixed group environment

DESIRABLE:

· M.S. Analytical Chemistry, Chemistry, Biochemistry or related field

· Ph.D. in Analytical Chemistry

· Proven track record of bioanalytical scientific achievement established through poster/oral presentation or publication in peer reviewed journals

· Basic understanding of pharmacokinetics and pharmacodynamics

· Experience in low flow rate LC-MS techniques

· Experience developing and/or applying low detection limit capability LC-MS techniques for drug compound or metabolite identification

· Supervisory experience

The ideal candidate will posess strong analytical and organizational skills, good interpersonal interactions and a desire for continually improving analytical processes.  Ability to work within, and support, a team environment is imperative.  Knowledge of drug metabolism fundamentals, such as metabolic stability and absorption is desired.    

Please email your CV/Resume to cv@mspeople.net